پیراسیٹامول: گردانَن مَنٛز فَرَق

وِکیٖپیٖڈیا پؠٹھٕ، اَکھ آزاد اِنسایکلوپیٖڈیا
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'''پیراسیٹامول'''، یتھ ا'''یسیٹامینوفین''' تہِ ونان چھِ، چھُ اکھ دوا یُس [[دَگ]] تہٕ [[تَپھ]] علاج کرنہٕ خٲطرٕ استعمال چھُ یِوان کرنہٕ۔<ref name="AHFS20162">{{cite web|title=Acetaminophen|url=https://www.drugs.com/monograph/acetaminophen.html|url-status=live|archive-url=https://web.archive.org/web/20160605063136/http://www.drugs.com/monograph/acetaminophen.html|archive-date=5 June 2016|access-date=16 September 2016|publisher=The American Society of Health-System Pharmacists}}</ref><ref name="pmid287349392">{{cite journal|last1=Lee|first1=WM|date=December 2017|title=Acetaminophen (APAP) hepatotoxicity-Isn't it time for APAP to go away?|journal=Journal of Hepatology|volume=67|issue=6|pages=1324–1331|doi=10.1016/j.jhep.2017.07.005|pmc=5696016|pmid=28734939}}</ref> یہِ چھُ عموٗمَن ہلکہٕ پؠٹھٕ درمیٲنی دَگہِ منٛز راحت باپتھ استعمال یِوان کرنہٕ۔<ref name="AHFS20162" /> کیٚنٛہہ ثبوٗتن ہُنٛد خیال چھُ زِ امہِ سٟتؠ چھِ تپھ وٲلؠ شُرؠ ٹھنڈ کرنس منٛز مدد مِلان، مگر باقٕے چھِنہٕ یوٗتاہ یقین تھاوان۔<ref>{{cite journal|vauthors=Meremikwu M, Oyo-Ita A|date=2002|title=Paracetamol for treating fever in children|journal=The Cochrane Database of Systematic Reviews|issue=2|pages=CD003676|doi=10.1002/14651858.CD003676|pmc=6532671|pmid=12076499}}</ref><ref>{{cite journal|vauthors=de Martino M, Chiarugi A|date=2015|title=Recent Advances in Pediatric Use of Oral Paracetamol in Fever and Pain Management|journal=Pain and Therapy|volume=4|issue=2|pages=149–168|doi=10.1007/s40122-015-0040-z|pmc=4676765|pmid=26518691}}</ref> یہِ چُھ اَکثَر باقٕے دَوہان سٟتؠ مِلِتھ کٕننہٕ یِوان، یِتھ کٔنہِ زن وارِیاہن سردی ہٕنٛد دَوا چھِ۔ <ref name="AHFS20162" /> پیراسیٹامول چھُ شٔدیٖد دَگہِ خٲطرٕ تہِ استعمال یِوان کرنہٕ، یِتھ کٔنؠ زَن کینسرٕچ دَگ تہٕ سرجری پتہٕ دَگ، اوپیئڈ دَگہِ ہٕنٛدِ دوا سٟتؠ مِلِتھ۔<ref>{{cite book|author=Scottish Intercollegiate Guidelines Network (SIGN)|title=Guideline 106: Control of pain in adults with cancer|publisher=National Health Service (NHS)|year=2008|isbn=9781905813384|location=Scotland|chapter=6.1 and 7.1.1|chapter-url=http://www.sign.ac.uk/pdf/SIGN106.pdf|archive-url=https://web.archive.org/web/20101220061154/http://sign.ac.uk/pdf/SIGN106.pdf|archive-date=20 December 2010|url-status=live|df=}}</ref> یہِ چُھ عموٗمَن یا تہِ ٲسہ کِن یا ریٚکٹہِ پٲٹھہِ اِستعمال کرنہٕ یِوان، مگر یہِ چُھ رَگہِ منٛز اِنٛجیٚکشَن ذٔریعہٕ تہِ دِنہٕ یِوان۔<ref name="AHFS20162" /><ref name="Hoch20142">{{cite book|last=Hochhauser|first=Daniel|url=https://books.google.com/books?id=CXjDBAAAQBAJ&pg=PA119|title=Cancer and its Management|date=2014|publisher=John Wiley & Sons|isbn=9781118468715|page=119|author-link=Daniel Hochhauser|archive-url=https://web.archive.org/web/20170908185107/https://books.google.com/books?id=CXjDBAAAQBAJ&pg=PA119|archive-date=8 September 2017|url-status=live}}</ref> اَمیُک اثر چُھ روزان دون پؠٹھ ژورن گھنٹن درمیان۔<ref name="Hoch20142" />
'''پیراسیٹامول'''، یَتھ ا'''یسیٹامینوفین''' تہِ ونان چھِ، چھُ اَکھ دوا یُس [[دَگ]] تہٕ [[تَپھ]] علاج کرنہٕ خٲطرٕ اِستِمال چھُ یِوان کرنہٕ۔<ref name="AHFS20162">{{cite web|title=Acetaminophen|url=https://www.drugs.com/monograph/acetaminophen.html|url-status=live|archive-url=https://web.archive.org/web/20160605063136/http://www.drugs.com/monograph/acetaminophen.html|archive-date=5 June 2016|access-date=16 September 2016|publisher=The American Society of Health-System Pharmacists}}</ref><ref name="pmid287349392">{{cite journal|last1=Lee|first1=WM|date=December 2017|title=Acetaminophen (APAP) hepatotoxicity-Isn't it time for APAP to go away?|journal=Journal of Hepatology|volume=67|issue=6|pages=1324–1331|doi=10.1016/j.jhep.2017.07.005|pmc=5696016|pmid=28734939}}</ref> یہِ چھُ عموٗمَن ہلکہٕ پؠٹھٕ درمیٲنی دَگہِ مَنٛز راحت باپتھ اِستِمال یِوان کرنہٕ۔<ref name="AHFS20162" /> کیٚنٛہہ ثبوٗتن ہُنٛد خیال چھُ زِ امہِ سٟتؠ چھِ تپھ وٲلؠ شُرؠ ٹھنڈ کرنس مَنٛز مدد مِلان، مگر باقٕے چھِنہٕ یوٗتاہ یقین تھاوان۔<ref>{{cite journal|vauthors=Meremikwu M, Oyo-Ita A|date=2002|title=Paracetamol for treating fever in children|journal=The Cochrane Database of Systematic Reviews|issue=2|pages=CD003676|doi=10.1002/14651858.CD003676|pmc=6532671|pmid=12076499}}</ref><ref>{{cite journal|vauthors=de Martino M, Chiarugi A|date=2015|title=Recent Advances in Pediatric Use of Oral Paracetamol in Fever and Pain Management|journal=Pain and Therapy|volume=4|issue=2|pages=149–168|doi=10.1007/s40122-015-0040-z|pmc=4676765|pmid=26518691}}</ref> یہِ چھُ اَکثَر باقٕے دَوہان سٟتؠ مِلِتھ کٕننہٕ یِوان، یِتھ کٔنہِ زن وارِیاہن سردی ہٕنٛد دَوا چھِ۔ <ref name="AHFS20162" /> پیراسیٹامول چھُ شٔدیٖد دَگہِ خٲطرٕ تہِ اِستِمال یِوان کرنہٕ، یِتھ کٔنؠ زَن کینسرٕچ دَگ تہٕ سرجری پتہٕ دَگ، اوپیئڈ دَگہِ ہٕنٛدِ دوا سٟتؠ مِلِتھ۔<ref>{{cite book|author=Scottish Intercollegiate Guidelines Network (SIGN)|title=Guideline 106: Control of pain in adults with cancer|publisher=National Health Service (NHS)|year=2008|isbn=9781905813384|location=Scotland|chapter=6.1 and 7.1.1|chapter-url=http://www.sign.ac.uk/pdf/SIGN106.pdf|archive-url=https://web.archive.org/web/20101220061154/http://sign.ac.uk/pdf/SIGN106.pdf|archive-date=20 December 2010|url-status=live|df=}}</ref> یہِ چھُ عموٗمَن یا تہِ ٲسہ کِن یا ریٚکٹہِ پٲٹھہِ اِستعمال کرنہٕ یِوان، مگر یہِ چھُ رَگہِ مَنٛز اِنٛجیٚکشَن ذٔریعہٕ تہِ دِنہٕ یِوان۔<ref name="AHFS20162" /><ref name="Hoch20142">{{cite book|last=Hochhauser|first=Daniel|url=https://books.google.com/books?id=CXjDBAAAQBAJ&pg=PA119|title=Cancer and its Management|date=2014|publisher=John Wiley & Sons|isbn=9781118468715|page=119|author-link=Daniel Hochhauser|archive-url=https://web.archive.org/web/20170908185107/https://books.google.com/books?id=CXjDBAAAQBAJ&pg=PA119|archive-date=8 September 2017|url-status=live}}</ref> اَمیُک اثر چھُ روزان دون پؠٹھ ژورن گھنٹن درمیان۔<ref name="Hoch20142" />


پیراسیٹامول چھُ عموٗمَن تجویٖز کرنہٕ آمٕژ خوراکَن پؠٹھ محفوٗظ۔<ref name="Rus20032">{{cite journal|vauthors=Russell FM, Shann F, Curtis N, Mulholland K|date=2003|title=Evidence on the use of paracetamol in febrile children|journal=Bulletin of the World Health Organization|volume=81|issue=5|pages=367–72|issn=0042-9686|pmc=2572451|pmid=12856055|hdl=10665/268935}}</ref> أکِس بالغ سٕنٛدِ خٲطرٕ چُھ تجویٖز کرنہٕ آمُت زِیٛادٕ کھۄتہٕ زِیٛادٕ دوذ ترے پؠٹھ ژور گرٛام۔<ref name="UK20172">{{Cite web|title=Paracetamol for adults: painkiller to treat aches, pains and fever|url=https://www.nhs.uk/medicines/paracetamol-for-adults/|url-status=live|archive-url=https://web.archive.org/web/20170822174155/https://beta.nhs.uk/medicines/paracetamol-for-adults|archive-date=22 August 2017|access-date=22 August 2017|website=[[National Health Service]]}}</ref><ref name="Med20182">{{cite web|title=What are the recommended maximum daily dosages of acetaminophen in adults and children?|url=https://www.medscape.com/answers/820200-27207/what-are-the-recommended-maximum-daily-dosages-of-acetaminophen-in-adults-and-children|url-status=live|archive-url=https://web.archive.org/web/20181221041534/https://www.medscape.com/answers/820200-27207/what-are-the-recommended-maximum-daily-dosages-of-acetaminophen-in-adults-and-children|archive-date=21 December 2018|access-date=19 December 2018|website=Medscape}}</ref><ref name="BMJ20152">{{cite journal|vauthors=Machado GC, Maher CG, Ferreira PH, Pinheiro MB, Lin CW, Day RO, McLachlan AJ, Ferreira ML|date=31 March 2015|title=Efficacy and safety of paracetamol for spinal pain and osteoarthritis: systematic review and meta-analysis of randomised placebo controlled trials.|journal=BMJ (Clinical Research Ed.)|volume=350|pages=h1225|doi=10.1136/bmj.h1225|pmc=4381278|pmid=25828856}}</ref> زیادٕ خۄراک ہیٚکہٕ زہریلہٕ ہنٛد بٲعث بنتھ،یَتھ مَنٛز جگر ناکام گژھَن شٲمِل چھُ۔<ref name="AHFS20162" /> مٕسلٕچ دَگ یۄس واریاہ شٔدیٖد چھِ تِم ہیٚکن کُنہِ ساتہٕ گٔژھِتھ، مگر یہِ چُھ نایاب آسان۔<ref name="AHFS20162" /> یہِ چُھ باسان حملس دوران تہٕ ماجہِ ہُنٛد دۄد دِنہٕ وِزِ محفوٗظ۔<ref name="AHFS20162" /> جگرٕچ بؠٲرؠ والیٚن منٛز ہیٚکو یہِ استعمال کٔرِتھ، مگر کم خوراکن منٛز۔<ref>{{cite journal|vauthors=Lewis JH, Stine JG|date=June 2013|title=Review article: prescribing medications in patients with cirrhosis - a practical guide|journal=Alimentary Pharmacology & Therapeutics|volume=37|issue=12|pages=1132–56|doi=10.1111/apt.12324|pmid=23638982}}</ref> اَتھ ہلکہٕ اینالجیسک پٲٹھؠ درجہٕ بندی کرنہٕ آمٔژ۔<ref name="Hoch20142" /> اَتھ منٛز چھَنہٕ ورمس خٕلاف زیادٕ سرگرمی۔<ref name="McK20132">{{cite book|last1=McKay|first1=Gerard A.|title=Lecture Notes Clinical Pharmacology and Therapeutics|last2=Walters|first2=Matthew R.|date=2013|publisher=Wiley|isbn=9781118344897|edition=9th|location=Hoboken|chapter=Non-Opioid Analgesics|access-date=5 August 2020|chapter-url=https://books.google.com/books?id=OGOqcfN_Cc8C&pg=PT353|archive-url=https://web.archive.org/web/20170908185108/https://books.google.com/books?id=OGOqcfN_Cc8C&pg=PT353|archive-date=8 September 2017|url-status=live}}</ref> یہٕ کِتھ کٔنؠ چُھ کٲم کران یہٕ چُھنہٕ مکمل طورس پیٹھ واضح۔<ref name="McK20132" /><ref name="Ghanem20162">{{cite journal|vauthors=Ghanem CI, Pérez MJ, Manautou JE, Mottino AD|date=July 2016|title=Acetaminophen from liver to brain: New insights into drug pharmacological action and toxicity.|journal=Pharmacological Research|volume=109|pages=119–31|doi=10.1016/j.phrs.2016.02.020|pmc=4912877|pmid=26921661}}</ref><ref name="pmid183814602">{{cite journal|vauthors=Viswanathan AN, Feskanich D, Schernhammer ES, Hankinson SE|year=2008|title=Aspirin, NSAID, and Acetaminophen Use and the Risk of Endometrial Cancer|journal=Cancer Research|volume=68|issue=7|pages=2507–2513|doi=10.1158/0008-5472.CAN-07-6257|pmc=2857531|pmid=18381460}}</ref>
پیراسیٹامول چھُ عموٗمَن تجویٖز کرنہٕ آمٕژ خوراکَن پؠٹھ محفوٗظ۔<ref name="Rus20032">{{cite journal|vauthors=Russell FM, Shann F, Curtis N, Mulholland K|date=2003|title=Evidence on the use of paracetamol in febrile children|journal=Bulletin of the World Health Organization|volume=81|issue=5|pages=367–72|issn=0042-9686|pmc=2572451|pmid=12856055|hdl=10665/268935}}</ref> أکِس بالغ سٕنٛدِ خٲطرٕ چھُ تجویٖز کرنہٕ آمُت زِیٛادٕ کھۄتہٕ زِیٛادٕ دوذ ترے پؠٹھ ژور گرٛام۔<ref name="UK20172">{{Cite web|title=Paracetamol for adults: painkiller to treat aches, pains and fever|url=https://www.nhs.uk/medicines/paracetamol-for-adults/|url-status=live|archive-url=https://web.archive.org/web/20170822174155/https://beta.nhs.uk/medicines/paracetamol-for-adults|archive-date=22 August 2017|access-date=22 August 2017|website=[[National Health Service]]}}</ref><ref name="Med20182">{{cite web|title=What are the recommended maximum daily dosages of acetaminophen in adults and children?|url=https://www.medscape.com/answers/820200-27207/what-are-the-recommended-maximum-daily-dosages-of-acetaminophen-in-adults-and-children|url-status=live|archive-url=https://web.archive.org/web/20181221041534/https://www.medscape.com/answers/820200-27207/what-are-the-recommended-maximum-daily-dosages-of-acetaminophen-in-adults-and-children|archive-date=21 December 2018|access-date=19 December 2018|website=Medscape}}</ref><ref name="BMJ20152">{{cite journal|vauthors=Machado GC, Maher CG, Ferreira PH, Pinheiro MB, Lin CW, Day RO, McLachlan AJ, Ferreira ML|date=31 March 2015|title=Efficacy and safety of paracetamol for spinal pain and osteoarthritis: systematic review and meta-analysis of randomised placebo controlled trials.|journal=BMJ (Clinical Research Ed.)|volume=350|pages=h1225|doi=10.1136/bmj.h1225|pmc=4381278|pmid=25828856}}</ref> زیٛادٕ خۄراک ہیٚکہٕ زہریلہٕ ہنٛد بٲعث بنتھ،یَتھ مَنٛز جگر ناکام گژھَن شٲمِل چھُ۔<ref name="AHFS20162" /> مٕسلٕچ دَگ یۄس واریاہ شٔدیٖد چھِ تِم ہیٚکن کُنہِ ساتہٕ گٔژھِتھ، مگر یہِ چھُ نایاب آسان۔<ref name="AHFS20162" /> یہِ چھُ باسان حملس دوران تہٕ ماجہِ ہُنٛد دۄد دِنہٕ وِزِ محفوٗظ۔<ref name="AHFS20162" /> جگرٕچ بؠٲرؠ والیٚن مَنٛز ہیٚکو یہِ اِستِمال کٔرِتھ، مگر کم خوراکن مَنٛز۔<ref>{{cite journal|vauthors=Lewis JH, Stine JG|date=June 2013|title=Review article: prescribing medications in patients with cirrhosis - a practical guide|journal=Alimentary Pharmacology & Therapeutics|volume=37|issue=12|pages=1132–56|doi=10.1111/apt.12324|pmid=23638982}}</ref> اَتھ ہلکہٕ اینالجیسک پٲٹھؠ درجہٕ بندی کرنہٕ آمٔژ۔<ref name="Hoch20142" /> اَتھ مَنٛز چھَنہٕ ورمس خٕلاف زیٛادٕ سرگرمی۔<ref name="McK20132">{{cite book|last1=McKay|first1=Gerard A.|title=Lecture Notes Clinical Pharmacology and Therapeutics|last2=Walters|first2=Matthew R.|date=2013|publisher=Wiley|isbn=9781118344897|edition=9th|location=Hoboken|chapter=Non-Opioid Analgesics|access-date=5 August 2020|chapter-url=https://books.google.com/books?id=OGOqcfN_Cc8C&pg=PT353|archive-url=https://web.archive.org/web/20170908185108/https://books.google.com/books?id=OGOqcfN_Cc8C&pg=PT353|archive-date=8 September 2017|url-status=live}}</ref> یہٕ کِتھ کٔنؠ چھُ کٲم کران یہٕ چُھنہٕ مکمل طورس پؠٹھ واضح۔<ref name="McK20132" /><ref name="Ghanem20162">{{cite journal|vauthors=Ghanem CI, Pérez MJ, Manautou JE, Mottino AD|date=July 2016|title=Acetaminophen from liver to brain: New insights into drug pharmacological action and toxicity.|journal=Pharmacological Research|volume=109|pages=119–31|doi=10.1016/j.phrs.2016.02.020|pmc=4912877|pmid=26921661}}</ref><ref name="pmid183814602">{{cite journal|vauthors=Viswanathan AN, Feskanich D, Schernhammer ES, Hankinson SE|year=2008|title=Aspirin, NSAID, and Acetaminophen Use and the Risk of Endometrial Cancer|journal=Cancer Research|volume=68|issue=7|pages=2507–2513|doi=10.1158/0008-5472.CAN-07-6257|pmc=2857531|pmid=18381460}}</ref>


پیراسیٹامول آو گۄڈٕنِچہِ لَٹہِ 1877 منٛز بناونہٕ ۔<ref>{{cite book|last1=Mangus|first1=Brent C.|url=https://books.google.com/books?id=tV72AAAAQBAJ&pg=PA39|title=Pharmacology application in athletic training|last2=Miller|first2=Michael G.|date=2005|publisher=F.A. Davis|isbn=9780803620278|location=Philadelphia, Pennsylvania|page=39|access-date=5 August 2020|archive-url=https://web.archive.org/web/20170908185108/https://books.google.com/books?id=tV72AAAAQBAJ&pg=PA39|archive-date=8 September 2017|url-status=live}}</ref> یہِ چھُ [[اَمریٖکہ|امریکہ]] تہٕ [[یوٗرَپ|یورپ]] دۄشوٕنی منٛز دَگ تہٕ تپھ خٲطرٕ سارِوٕے کھۄتہٕ زِیٛادٕ استعمال گژھَن وول دوا ۔<ref>{{cite book|last=Aghababian|first=Richard V.|url=https://books.google.com/books?id=HnbKaRQAXOIC&pg=PA814|title=Essentials of emergency medicine|date=22 October 2010|publisher=Jones & Bartlett Publishers|isbn=978-1-4496-1846-9|page=814|archive-url=https://web.archive.org/web/20160817202827/https://books.google.com/books?id=HnbKaRQAXOIC&pg=PA814|archive-date=17 August 2016|url-status=live}}</ref> یہِ چھُ ورلڈ ہیلتھ آرگنائزیشن کِس ضروٗری ادوِیاتن ہِنٛدِس فہرستَس منٛز شٲمِل۔<ref name="WHO21st2">{{cite book|title=World Health Organization model list of essential medicines: 21st list 2019|vauthors=((World Health Organization))|publisher=World Health Organization|year=2019|location=Geneva|hdl=10665/325771|id=WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO|author-link=World Health Organization|hdl-access=free}}</ref> پیراسیٹامول چھُ اکھ عام دواہ پٲٹھؠ دٔستِیاب، یَتھ منٛز برانڈٕک ناو چھِ یِمَن منٛز ٹایلینول تہٕ پاناڈول تہِ شٲمِل چھِ۔<ref>{{cite book|last1=Hamilton|first1=Richard J.|url=https://books.google.com/books?id=lwueJ4IAl4oC&pg=PA12|title=Tarascon pocket pharmacopoeia : 2013 classic shirt-pocket edition|date=2013|publisher=Jones & Bartlett Learning|isbn=9781449665869|edition=27th|location=Burlington, Massachusetts|page=12|archive-url=https://web.archive.org/web/20170908185107/https://books.google.com/books?id=lwueJ4IAl4oC&pg=PA12|archive-date=8 September 2017|url-status=live}}</ref> 2017 ہَس منٛز اوس یہِ امریکہَس منٛز 25 ہِم سارِوٕے کھۄتہٕ زِیٛادٕ تجویٖز کرنہٕ آمُت دوا یَتھ منٛز 24 ملین کھۄتہٕ زِیٛادٕ نسخہٕ ٲسؠ۔<ref>{{cite web|title=The Top 300 of 2020|url=https://clincalc.com/DrugStats/Top300Drugs.aspx|url-status=live|archive-url=https://web.archive.org/web/20210212142534/https://clincalc.com/DrugStats/Top300Drugs.aspx|archive-date=12 February 2021|access-date=25 February 2020|publisher=ClinCalc}}</ref><ref>{{cite web|title=Acetaminophen Drug Usage Statistics|url=https://clincalc.com/DrugStats/Drugs/Acetaminophen|url-status=live|archive-url=https://web.archive.org/web/20200412005634/https://clincalc.com/DrugStats/Drugs/Acetaminophen|archive-date=12 April 2020|access-date=11 April 2020|website=ClinCalc}}</ref>
پیراسیٹامول آو گۄڈٕنِچہِ لَٹہِ 1877 مَنٛز بناونہٕ ۔<ref>{{cite book|last1=Mangus|first1=Brent C.|url=https://books.google.com/books?id=tV72AAAAQBAJ&pg=PA39|title=Pharmacology application in athletic training|last2=Miller|first2=Michael G.|date=2005|publisher=F.A. Davis|isbn=9780803620278|location=Philadelphia, Pennsylvania|page=39|access-date=5 August 2020|archive-url=https://web.archive.org/web/20170908185108/https://books.google.com/books?id=tV72AAAAQBAJ&pg=PA39|archive-date=8 September 2017|url-status=live}}</ref> یہِ چھُ [[اَمریٖکہ|امریکہ]] تہٕ [[یوٗرَپ|یورپ]] دۄشوٕنی مَنٛز دَگ تہٕ تپھ خٲطرٕ سارِوٕے کھۄتہٕ زِیٛادٕ اِستِمال گژھَن وول دوا ۔<ref>{{cite book|last=Aghababian|first=Richard V.|url=https://books.google.com/books?id=HnbKaRQAXOIC&pg=PA814|title=Essentials of emergency medicine|date=22 October 2010|publisher=Jones & Bartlett Publishers|isbn=978-1-4496-1846-9|page=814|archive-url=https://web.archive.org/web/20160817202827/https://books.google.com/books?id=HnbKaRQAXOIC&pg=PA814|archive-date=17 August 2016|url-status=live}}</ref> یہِ چھُ ورلڈ ہیلتھ آرگنائزیشن کِس ضروٗری ادوِیاتن ہِنٛدِس فہرستَس مَنٛز شٲمِل۔<ref name="WHO21st2">{{cite book|title=World Health Organization model list of essential medicines: 21st list 2019|vauthors=((World Health Organization))|publisher=World Health Organization|year=2019|location=Geneva|hdl=10665/325771|id=WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO|author-link=World Health Organization|hdl-access=free}}</ref> پیراسیٹامول چھُ اَکھ عام دواہ پٲٹھؠ دٔستِیاب، یَتھ مَنٛز برانڈٕک ناو چھِ یِمَن مَنٛز ٹایلینول تہٕ پاناڈول تہِ شٲمِل چھِ۔<ref>{{cite book|last1=Hamilton|first1=Richard J.|url=https://books.google.com/books?id=lwueJ4IAl4oC&pg=PA12|title=Tarascon pocket pharmacopoeia : 2013 classic shirt-pocket edition|date=2013|publisher=Jones & Bartlett Learning|isbn=9781449665869|edition=27th|location=Burlington, Massachusetts|page=12|archive-url=https://web.archive.org/web/20170908185107/https://books.google.com/books?id=lwueJ4IAl4oC&pg=PA12|archive-date=8 September 2017|url-status=live}}</ref> 2017 ہَس مَنٛز اوس یہِ امریکہَس مَنٛز 25 ہِم سارِوٕے کھۄتہٕ زِیٛادٕ تجویٖز کرنہٕ آمُت دوا یَتھ مَنٛز 24 ملین کھۄتہٕ زِیٛادٕ نسخہٕ ٲسؠ۔<ref>{{cite web|title=The Top 300 of 2020|url=https://clincalc.com/DrugStats/Top300Drugs.aspx|url-status=live|archive-url=https://web.archive.org/web/20210212142534/https://clincalc.com/DrugStats/Top300Drugs.aspx|archive-date=12 February 2021|access-date=25 February 2020|publisher=ClinCalc}}</ref><ref>{{cite web|title=Acetaminophen Drug Usage Statistics|url=https://clincalc.com/DrugStats/Drugs/Acetaminophen|url-status=live|archive-url=https://web.archive.org/web/20200412005634/https://clincalc.com/DrugStats/Drugs/Acetaminophen|archive-date=12 April 2020|access-date=11 April 2020|website=ClinCalc}}</ref>


== حوالہٕ ==
== حَوالہٕ ==
{{حَوالہٕ}}
{{حَوالہٕ}}

گَردان 18:00, 18 فَرؤری 2024 بَجے

پیراسیٹامول، یَتھ ایسیٹامینوفین تہِ ونان چھِ، چھُ اَکھ دوا یُس دَگ تہٕ تَپھ علاج کرنہٕ خٲطرٕ اِستِمال چھُ یِوان کرنہٕ۔[1][2] یہِ چھُ عموٗمَن ہلکہٕ پؠٹھٕ درمیٲنی دَگہِ مَنٛز راحت باپتھ اِستِمال یِوان کرنہٕ۔[1] کیٚنٛہہ ثبوٗتن ہُنٛد خیال چھُ زِ امہِ سٟتؠ چھِ تپھ وٲلؠ شُرؠ ٹھنڈ کرنس مَنٛز مدد مِلان، مگر باقٕے چھِنہٕ یوٗتاہ یقین تھاوان۔[3][4] یہِ چھُ اَکثَر باقٕے دَوہان سٟتؠ مِلِتھ کٕننہٕ یِوان، یِتھ کٔنہِ زن وارِیاہن سردی ہٕنٛد دَوا چھِ۔ [1] پیراسیٹامول چھُ شٔدیٖد دَگہِ خٲطرٕ تہِ اِستِمال یِوان کرنہٕ، یِتھ کٔنؠ زَن کینسرٕچ دَگ تہٕ سرجری پتہٕ دَگ، اوپیئڈ دَگہِ ہٕنٛدِ دوا سٟتؠ مِلِتھ۔[5] یہِ چھُ عموٗمَن یا تہِ ٲسہ کِن یا ریٚکٹہِ پٲٹھہِ اِستعمال کرنہٕ یِوان، مگر یہِ چھُ رَگہِ مَنٛز اِنٛجیٚکشَن ذٔریعہٕ تہِ دِنہٕ یِوان۔[1][6] اَمیُک اثر چھُ روزان دون پؠٹھ ژورن گھنٹن درمیان۔[6]

پیراسیٹامول چھُ عموٗمَن تجویٖز کرنہٕ آمٕژ خوراکَن پؠٹھ محفوٗظ۔[7] أکِس بالغ سٕنٛدِ خٲطرٕ چھُ تجویٖز کرنہٕ آمُت زِیٛادٕ کھۄتہٕ زِیٛادٕ دوذ ترے پؠٹھ ژور گرٛام۔[8][9][10] زیٛادٕ خۄراک ہیٚکہٕ زہریلہٕ ہنٛد بٲعث بنتھ،یَتھ مَنٛز جگر ناکام گژھَن شٲمِل چھُ۔[1] مٕسلٕچ دَگ یۄس واریاہ شٔدیٖد چھِ تِم ہیٚکن کُنہِ ساتہٕ گٔژھِتھ، مگر یہِ چھُ نایاب آسان۔[1] یہِ چھُ باسان حملس دوران تہٕ ماجہِ ہُنٛد دۄد دِنہٕ وِزِ محفوٗظ۔[1] جگرٕچ بؠٲرؠ والیٚن مَنٛز ہیٚکو یہِ اِستِمال کٔرِتھ، مگر کم خوراکن مَنٛز۔[11] اَتھ ہلکہٕ اینالجیسک پٲٹھؠ درجہٕ بندی کرنہٕ آمٔژ۔[6] اَتھ مَنٛز چھَنہٕ ورمس خٕلاف زیٛادٕ سرگرمی۔[12] یہٕ کِتھ کٔنؠ چھُ کٲم کران یہٕ چُھنہٕ مکمل طورس پؠٹھ واضح۔[12][13][14]

پیراسیٹامول آو گۄڈٕنِچہِ لَٹہِ 1877 مَنٛز بناونہٕ ۔[15] یہِ چھُ امریکہ تہٕ یورپ دۄشوٕنی مَنٛز دَگ تہٕ تپھ خٲطرٕ سارِوٕے کھۄتہٕ زِیٛادٕ اِستِمال گژھَن وول دوا ۔[16] یہِ چھُ ورلڈ ہیلتھ آرگنائزیشن کِس ضروٗری ادوِیاتن ہِنٛدِس فہرستَس مَنٛز شٲمِل۔[17] پیراسیٹامول چھُ اَکھ عام دواہ پٲٹھؠ دٔستِیاب، یَتھ مَنٛز برانڈٕک ناو چھِ یِمَن مَنٛز ٹایلینول تہٕ پاناڈول تہِ شٲمِل چھِ۔[18] 2017 ہَس مَنٛز اوس یہِ امریکہَس مَنٛز 25 ہِم سارِوٕے کھۄتہٕ زِیٛادٕ تجویٖز کرنہٕ آمُت دوا یَتھ مَنٛز 24 ملین کھۄتہٕ زِیٛادٕ نسخہٕ ٲسؠ۔[19][20]

حَوالہٕ

  1. ↑ 1٫0 1٫1 1٫2 1٫3 1٫4 1٫5 1٫6 "Acetaminophen". The American Society of Health-System Pharmacists. Archived from the original on 5 June 2016. Retrieved 16 September 2016.
  2. ↑ Lee، WM (December 2017). "Acetaminophen (APAP) hepatotoxicity-Isn't it time for APAP to go away?". Journal of Hepatology. 67 (6): 1324–1331. doi:10.1016/j.jhep.2017.07.005. PMC 5696016. PMID 28734939.
  3. ↑ Meremikwu M، Oyo-Ita A (2002). "Paracetamol for treating fever in children". The Cochrane Database of Systematic Reviews (2): CD003676. doi:10.1002/14651858.CD003676. PMC 6532671. PMID 12076499.
  4. ↑ de Martino M، Chiarugi A (2015). "Recent Advances in Pediatric Use of Oral Paracetamol in Fever and Pain Management". Pain and Therapy. 4 (2): 149–168. doi:10.1007/s40122-015-0040-z. PMC 4676765. PMID 26518691.
  5. ↑ Scottish Intercollegiate Guidelines Network (SIGN) (2008). "6.1 and 7.1.1" (PDF). Guideline 106: Control of pain in adults with cancer. Scotland: National Health Service (NHS). ISBN 9781905813384. Archived (PDF) from the original on 20 December 2010.
  6. ↑ 6٫0 6٫1 6٫2 Hochhauser، Daniel (2014). Cancer and its Management. John Wiley & Sons. ص. 119. ISBN 9781118468715. Archived from the original on 8 September 2017.
  7. ↑ Russell FM، Shann F، Curtis N، Mulholland K (2003). "Evidence on the use of paracetamol in febrile children". Bulletin of the World Health Organization. 81 (5): 367–72. hdl:10665/268935. ISSN 0042-9686. PMC 2572451. PMID 12856055.
  8. ↑ "Paracetamol for adults: painkiller to treat aches, pains and fever". National Health Service. Archived from the original on 22 August 2017. Retrieved 22 August 2017.
  9. ↑ "What are the recommended maximum daily dosages of acetaminophen in adults and children?". Medscape. Archived from the original on 21 December 2018. Retrieved 19 December 2018.
  10. ↑ Machado GC، Maher CG، Ferreira PH، Pinheiro MB، Lin CW، Day RO، McLachlan AJ، Ferreira ML (31 March 2015). "Efficacy and safety of paracetamol for spinal pain and osteoarthritis: systematic review and meta-analysis of randomised placebo controlled trials". BMJ (Clinical Research Ed.). 350: h1225. doi:10.1136/bmj.h1225. PMC 4381278. PMID 25828856.
  11. ↑ Lewis JH، Stine JG (June 2013). "Review article: prescribing medications in patients with cirrhosis - a practical guide". Alimentary Pharmacology & Therapeutics. 37 (12): 1132–56. doi:10.1111/apt.12324. PMID 23638982.
  12. ↑ 12٫0 12٫1 McKay، Gerard A.؛ Walters، Matthew R. (2013). "Non-Opioid Analgesics". Lecture Notes Clinical Pharmacology and Therapeutics (9th ed.). Hoboken: Wiley. ISBN 9781118344897. Archived from the original on 8 September 2017. Retrieved 5 August 2020.
  13. ↑ Ghanem CI، Pérez MJ، Manautou JE، Mottino AD (July 2016). "Acetaminophen from liver to brain: New insights into drug pharmacological action and toxicity". Pharmacological Research. 109: 119–31. doi:10.1016/j.phrs.2016.02.020. PMC 4912877. PMID 26921661.
  14. ↑ Viswanathan AN، Feskanich D، Schernhammer ES، Hankinson SE (2008). "Aspirin, NSAID, and Acetaminophen Use and the Risk of Endometrial Cancer". Cancer Research. 68 (7): 2507–2513. doi:10.1158/0008-5472.CAN-07-6257. PMC 2857531. PMID 18381460.
  15. ↑ Mangus، Brent C.؛ Miller، Michael G. (2005). Pharmacology application in athletic training. Philadelphia, Pennsylvania: F.A. Davis. ص. 39. ISBN 9780803620278. Archived from the original on 8 September 2017. Retrieved 5 August 2020.
  16. ↑ Aghababian، Richard V. (22 October 2010). Essentials of emergency medicine. Jones & Bartlett Publishers. ص. 814. ISBN 978-1-4496-1846-9. Archived from the original on 17 August 2016.
  17. ↑ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
  18. ↑ Hamilton، Richard J. (2013). Tarascon pocket pharmacopoeia : 2013 classic shirt-pocket edition (27th ed.). Burlington, Massachusetts: Jones & Bartlett Learning. ص. 12. ISBN 9781449665869. Archived from the original on 8 September 2017.
  19. ↑ "The Top 300 of 2020". ClinCalc. Archived from the original on 12 February 2021. Retrieved 25 February 2020.
  20. ↑ "Acetaminophen Drug Usage Statistics". ClinCalc. Archived from the original on 12 April 2020. Retrieved 11 April 2020.
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